Identifying spatial immuno-oncological parameters of mouse tumors using Imaging Mass Cytometry

Immuno-PET Imaging of Engineered Human T Cells in Tumors.

Sensitive in vivo imaging technologies applicable to the clinical setting are still lacking for adoptive T-cell-based immunotherapies, an important gap to fill if mechanisms of tumor rejection or escape are to be understood. Here, we propose a highly sensitive imaging technology to track human TCR-transgenic T cells in vivo by directly targeting the murinized constant TCR beta domain (TCRmu) wi...

Identifying Structural Parameters of Social " Processes Using

In this paper we present examples illustrating five important issues involved in the identification of structural information about social processes using the fragmentary data which is usually available for this purpose. These issues are listed below. (i) It is of considerable importance to use continuous-time models to desi;ribe processes for which there is no substant~ve basis for a choice of...

Determination of experimental Tumor Volume of a mouse using optical imaging system in different processing stages

Spatial Localization and Quantitation of Androgens in Mouse Testis by Mass Spectrometry Imaging

Androgens are essential for male development and reproductive function. They are transported to their site of action as blood-borne endocrine hormones but can also be produced within tissues to act in intracrine and paracrine fashions. Because of this, circulating concentrations may not accurately reflect the androgenic influence within specific tissue microenvironments. Mass spectrometry imagi...

Recent advances in oncological imaging

important in the management of patients with cancer, reflecting a growing need to evaluate disease status not only at the time of diagnosis and staging, but also at regular intervals during treatment follow-up. Imaging is a rapidly evolving medical specialty based on technical innovations and continues to take on new roles in clinical medicine. Close co-operation between clinicians and radiolog...